When I think about the animals of the Empty Quarter, I think of something like the above clip.
Or maybe this…
…but not a lot of this.
Unless you want to go full Dune in your Traveller Universe, sandworms don’t have a real place there, in addition to being physically impossible in terrestrial worlds. (Waterworlds, Gas Giants, and low-grav atmospheres are a different matter.)
Ignoring reality in favour of drama, sandworms would be great to see in the desert-oriented Imperial subsectors, but the Empty Quarter isn’t wealthy or important enough for the equivalent of Spice (or Oil, for that matter) to be of great abundance there.